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Those effects include euphoria and drowsiness, as well as slowing of the pulse. He was taking significant amounts of prescribed pain medication, including Tylox (acetaminophen, 500 mg, and oxycodone HCI, 5 mg) and Vicodin (acetaminophen, 500 mg, and hydrocodone bitartrate, 5 mg). You may take the medication with food or milk if it causes stomach upset. Do not vicodin 5 500 use this medication without telling your doctor if you are breast-feeding a baby. It has Vicodin 5 500 been found that use of these drugs is more prevalent in mid-western, non-urban areas.